Prof. Yoo-Wook Kwon
Yoo-Wook Kwon, Ph.D
Associate Professor
Biomedical Research Institute, Seoul National University Hospital
Department of Internal Medicine, Seoul National University College of Medicine
101 Daehang-ro (28 Yeongeon-dong), Jongno-gu, Seoul 110-744, Korea
Tel: (82)-2-740-8917, E-Mail: ywkwon@snu.ac.kr
Dr. Yoo-Wook Kwon now is an associated professor, Seoul National University and Seoul National University Hospital. He earned his B.Sc., M.Sc. and Ph.D. in Molecular Biology at Pusan National University. From 1991 to 2001, Dr. Kwon worked with Dr. Lobanenkov Victor in Epigenetics and Mechanism study of CTCF at the National Institute of Health, USA. He found novel function of CTCF in Enhancer and investigated the mechanism. Since then, he moved to the Korea, joining Seoul National University Hospital, working on stem cell biology, inflammation and cell metabolism. He found novel receptor for resistin and published in Cell Metabolism. And he developed very efficient method to generate protein derived iPS cells and induced cardiomyocytes (iCM).
Representative Publications:
1. Yujung Chang, Euiyeon Lee, Junyeop Kim, Yoo-Wook Kwon*, Youngeun Kwon*, Jongpil Kim*. Efficient in vivo direct conversion of fibroblasts into cardiomyocytes using a nanoparticle-based gene carrier. Biomaterials. In press [IF=8.806] *Corresponding
2. Kwon YW, et al. Imprinted gene Zinc finger protein 127 is a novel regulator of master pluripotency transcription factor, Oct4. BMB Rep. ;51(5):242-248. [IF=3.089]
3. Moon-Yong Cha,†, Yoo-Wook Kwon†, et al. Protein-iPSCs ameliorate cognitive dysfunction and reduce Aβ deposition in a mouse model of Alzheimer’s disease. Stem cells translational medicine. 6(1):293-305, 2017. [IF=4.247] †These authors contributed equally to this work.
4. Kwon YW, et al. E-Ras improves the efficiency of reprogramming by facilitating cell cycle progression through JNK-Sp1 pathway. Stem Cell Res. 16;15(3):481-494, 2015 [IF=3.892]
5. Kwon YW*, et al. Role of Zscan4 in secondary murine iPSC derivation mediated by protein extracts of ESC or iPSC. Biomaterials. 59, 102-115, 2015 [IF=8.387]
6. Sahmin Lee,* Hyun-Chae Lee,* Yoo-Wook Kwon,* et al. Adenylyl Cyclase-Associated Protein 1(CAP1) is a Receptor for Human Resistin and Mediates Inflammatory Actions of Human Monocytes. Cell Metabolism 19, 484-497, 2014 [IF=18.164] *These authors contributed equally to this work.
7. Han JK, Kwon YW, et al. Direct Conversion of Adult Skin Fibroblasts to Endothelial Cells by Defined Factors. Circulation. 130(14), 1168-78, 2014 [IF=17.047]
Associate Professor
Biomedical Research Institute, Seoul National University Hospital
Department of Internal Medicine, Seoul National University College of Medicine
101 Daehang-ro (28 Yeongeon-dong), Jongno-gu, Seoul 110-744, Korea
Tel: (82)-2-740-8917, E-Mail: ywkwon@snu.ac.kr
Dr. Yoo-Wook Kwon now is an associated professor, Seoul National University and Seoul National University Hospital. He earned his B.Sc., M.Sc. and Ph.D. in Molecular Biology at Pusan National University. From 1991 to 2001, Dr. Kwon worked with Dr. Lobanenkov Victor in Epigenetics and Mechanism study of CTCF at the National Institute of Health, USA. He found novel function of CTCF in Enhancer and investigated the mechanism. Since then, he moved to the Korea, joining Seoul National University Hospital, working on stem cell biology, inflammation and cell metabolism. He found novel receptor for resistin and published in Cell Metabolism. And he developed very efficient method to generate protein derived iPS cells and induced cardiomyocytes (iCM).
Representative Publications:
1. Yujung Chang, Euiyeon Lee, Junyeop Kim, Yoo-Wook Kwon*, Youngeun Kwon*, Jongpil Kim*. Efficient in vivo direct conversion of fibroblasts into cardiomyocytes using a nanoparticle-based gene carrier. Biomaterials. In press [IF=8.806] *Corresponding
2. Kwon YW, et al. Imprinted gene Zinc finger protein 127 is a novel regulator of master pluripotency transcription factor, Oct4. BMB Rep. ;51(5):242-248. [IF=3.089]
3. Moon-Yong Cha,†, Yoo-Wook Kwon†, et al. Protein-iPSCs ameliorate cognitive dysfunction and reduce Aβ deposition in a mouse model of Alzheimer’s disease. Stem cells translational medicine. 6(1):293-305, 2017. [IF=4.247] †These authors contributed equally to this work.
4. Kwon YW, et al. E-Ras improves the efficiency of reprogramming by facilitating cell cycle progression through JNK-Sp1 pathway. Stem Cell Res. 16;15(3):481-494, 2015 [IF=3.892]
5. Kwon YW*, et al. Role of Zscan4 in secondary murine iPSC derivation mediated by protein extracts of ESC or iPSC. Biomaterials. 59, 102-115, 2015 [IF=8.387]
6. Sahmin Lee,* Hyun-Chae Lee,* Yoo-Wook Kwon,* et al. Adenylyl Cyclase-Associated Protein 1(CAP1) is a Receptor for Human Resistin and Mediates Inflammatory Actions of Human Monocytes. Cell Metabolism 19, 484-497, 2014 [IF=18.164] *These authors contributed equally to this work.
7. Han JK, Kwon YW, et al. Direct Conversion of Adult Skin Fibroblasts to Endothelial Cells by Defined Factors. Circulation. 130(14), 1168-78, 2014 [IF=17.047]
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